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Wednesday, January 22, 2020

PCV 10 and PCV 13 vaccines can save your child's life

My kids were vaccinated from childbirth until their teenage years. Since I worked in a hospital, immunization is free of charge to us, regular employees. I was just thankful that all of my  children (who are now grown ups)  availed all the vaccination and shots they needed during their growing up years. 

My children's pediatrician thought us that vaccinations not only protect your child from deadly diseases, such as polio, tetanus, and diphtheria, but they also keep other children safe by eliminating  dangerous diseases that used to spread from child to child. I remember my kids had the shots from BCG, DPT to boosters. I thanked God that they never had a complicated disease up to this day and was only hospitalized twice due to viral diagnoses. 

As of this writing I wasnt fully aware of PCV 10 and PCV 13 vaccines.  It was  only during a public health forum held at Manila Hotel that speaker Dr. Lulu Bravo informed us of the importance of the said vaccinations. PCV 13 is available from your Pediatrician from around P3k to P3500 per shot, it depends on the manufacturer or pharma. 

PCV is pneumococcal conjugate vaccines. Two pneumococcal conjugate vaccines (PCVs) are currently licensed for infant vaccination against pneumococcus. 13-valent PCV (PCV13) and  Ten-valent PCV (PCV10). 
In layman's term, it protect against pneumococcal infections, which are caused by bacteria. The bacteria spread through person-to-person contact and can cause such serious infections as pneumonia, blood infections, and bacterial meningitis which are all deadly. 

Dr. Lulu Bravo, Executive Director of the Philippine Foundation for Vaccination joined by Atty. Tom Syquija, former Executive Director of Procurement Service- Philippine Government Electronic Procurement System (PS-PhilGEPS) helped us educate why is there a need for PCV 10 and PCV 13 to be administered and that a public bidding is needed for procurement of the said vaccines. 

A stronger push towards more competitive bidding is key to regaining public confidence in vaccines, said experts from both the public and private sector during a public health forum held at the Manila Hotel last Wednesday.

It's always best to have a public bidding, because competition will give you the best price. It is transparent,” noted Tom Syquija, former Executive Director of Procurement Service- Philippine Government Electronic Procurement System (PS-PhilGEPS). “You get the same quality but at the lowest price. It's always best for the public if you have competition,” he added.

The budget for pneumonia vaccines alone is P4.9 billion, allotted for Pneumococcal Conjugate Vaccines (PCVs), which aim to guard against Invasive Pneumococcal Diseases (IPDs), the largest cause of death for Filipino children under five. 

Currently, there are two vaccines available for the government to procure during the next budget allocation, PCV 10 and PCV 13, two vaccines that global health experts claim are comparable in performance.

In February 2019, the World Health Organization (WHO) reaffirmed an earlier position saying that the two available PCVs are equally effective in preventing overall pneumococcal diseases in children. The position paper also states that there is at present insufficient evidence of a difference in the net impact of the two available PCVs on overall disease burden.

The WHO has already come out saying that there’s really no difference between the two,” said Dr. Lulu Bravo, Executive Director of the Philippine Foundation for Vaccination, when discussing the efficacy of the two PCVs. “Many developing countries have already procured PCV 10.”

Similarly, the Pan-American Health Organization (PAHO) in its own study said that available evidence to date indicates significant impact of both PCV10 and PCV13 in the outcomes studied, with no evidence of the superiority of one vaccine over the other on pneumonia, Invasive Pneumococcal Diseases (IPD), or meningitis hospitalization reduction in children under 5 years old.

In turn, the International Vaccine Access Center (IVAC), in their 2017 PCV product assessment which was based on a comprehensive review of published data, also declared that current evidence does not indicate an added benefit with one vaccine over the other.

Syquija highlighted that the competitive bidding process should be accompanied by the scrutiny and recommendation of legitimate health experts, which would help allay concerns over whether the procured vaccine has carefully been studied or not.

“The first thing to ask is, what is appropriate for the Philippines? How many manufacturers make PCV13? How many PCV10?” said Syquija. “You need a decision on an expert level. What product do we need? Then it will dictate the modality of the procurement.”

Even when the procurement process is transparent, there is a danger in the way it is implemented, claimed Syquija. The bid posted by the government is required to list specifications regarding the item to be procured. It is possible to “tailor-fit” the bid by listing specifications that unnecessarily cut other options out, making it difficult to protect the sanctity of the contract.

“Do we need a PCV10? If that is sufficient, and has multiple suppliers, why would you go for 13 if there is only one (supplier)?” he said.

There is also a concern among health experts that the resurgence of diseases and the potential exacerbation of currently prominent sicknesses, like pneumonia and meningitis, will become a larger problem should the public's fear towards vaccines continues to persist.

Experts believe that vaccine confidence is a critical issue, especially since pneumonia is a very common disease in children here and abroad. Of the hundreds of countries in the world, the Philippines is included in the top 15 countries in terms of pneumonia deaths, and those 15 countries are responsible for 75% of all deaths from pneumonia.

“In the last year or so we had so many outbreaks. Since 2018, nawala ang vaccine confidence ng Pilipinas. Isa tayong country na naging number one anti-vaccine country in the world,” said Dr. Bravo, “The vaccine confidence of 93% in 2015 plunged to 30 percent in 2018.”

“Patients, people, and the community, would drive away the healthcare workers. They were being stoned, they were being driven away, and were even called child-killers,” she added.

In an earlier statement, the DOH pointed to vaccine hesitancy, or the refusal of vaccines despite availability, as one of the reasons for the recent measles outbreak in some regions of the country.

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