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Friday, June 30, 2023

Boehringer Ingelheim launches topical parasite treatment for cats



Boehringer Ingelheim, a global leader in animal health, has launched the parasite treatment, NexGard® COMBO for cats. With nearly 20 years of expertise in preventing parasites such as fleas, ticks, Lyme disease and more in dogs, NexGard® now adds a feline-specific product to the NexGard® family. The new treatment is designed to safeguard cats from a wider range of parasites than any other product on the market, covering both external parasites and internal parasites such as fleas, ticks, ear mites, face mange, hookworm, roundworm, vesical worm, lungworm, heartworm prevention, as well as tapeworm infections that affect their health and quality of life.

NexGard® COMBO for cats is a one-and-done, easy-to-use formula with the eprinomectin, praziquantel and next-generation active antiparasitic ingredient: esafoxolaner, which has been specially formulated for cats.

Parasite infections are common in cats and prevalent across Asia. According to an epidemiological study of over 1,000 cats in eastern and Southeast Asia, 43% of pet cats suffer from external parasites such as fleas, ticks and mites and 14% harbour deadly internal parasites such as hookworm, heartworm and roundworm.[i]

“Boehringer Ingelheim has always been on the cutting edge of research and development in the parasiticide space. Trusted by pet owners and veterinarians alike, our NexGard® family of products is currently ranked top in pet parasiticide sales worldwide. In Asia where over 26% of pet owners have cats[ii], we are thrilled to expand our feline parasite prevention line-up, which includes Broadline® and FRONTLINE PLUS® Cat, with NexGard® COMBO for cats. It is an innovative one-and-done formula with esafoxolaner, the first isoxazoline parasiticide formulated for cats plus eprinomectin and praziquantel for the broadest external and internal parasite coverage to date,” said Sukje Sung, Head of Boehringer Ingelheim Animal Health Philippines, Inc.

Common misconceptions about parasites in cats

Parasite infections are often disregarded as trivial issues but can cause serious health complications in cats such as bloody diarrhoea, dehydration, skin inflammation and anaemia. Ear mites are common causes of feline ear infections which are often picked up when roaming outdoors and can cause itchiness, inflammation and swelling of the ear canal.3 Additionally, some internal parasites such as hookworms can attach themselves to the intestines and to feed on the blood of cats. Left untreated, hookworm infections can result in potentially life-threatening blood loss, weakness, and malnutrition.4

Despite the high prevalence of parasite infections, many pet owners remain unaware of how common they are. In fact, according to veterinary specialist Dr. Ross Antonio Banayo, Technical Manager for the Companion Animal Business Segment of Boehringer Ingelheim Animal Health Philippines, Inc. pet owners remain misinformed about how these parasites are transmitted and impact their cats. These common misconceptions include: 

      Cats that are kept indoors are not susceptible to parasite infections and do not require regular veterinary visits.

      Cats only require treatment when they are infected with parasites. Preventive treatment is not necessary.

      Parasite infections are self-limiting and do not cause serious health issues.

      Removal of ticks and fleas can be effectively managed with parasite prevention shampoos alone.

According to Dr. Ross Antonio Banayo, Technical Manager for the Companion Animal Business Segment of Boehringer Ingelheim Animal Health Philippines, Inc. “Parasite infections can be particularly dangerous for cats. Common feline behaviours like grooming and roaming outdoors put them at a higher risk of contracting a variety of parasites. Often, cats only present with symptoms much later into the infection, resulting in worse complications. This highlights the need for us to change perceptions and move towards a preventive approach to parasite infections to safeguard their health.”

Parasites can be transmitted and affect human health too

Parasite infections not only impact the health of cats but can be transmitted to humans to cause complications such as skin infections, anaemia, gastrointestinal disturbances and more. Fortunately, transmission can be effectively prevented by administering regular parasiticide treatment for cats and adhering to regular follow-ups with a veterinarian. 

“The lives of pets and humans are so deeply interconnected that their health issues can impact our own. Just as we are shifting towards a preventive approach to human health, NexGard® COMBO is our preventive solution to preserve the health of cats. It represents the next step that we are taking to improve the health of animals across the region and drive a positive impact on our own health into the future,” said Sung.

Important Safety Information 

NexGard® COMBO is for topical use only in cats. The most frequently reported adverse reactions include vomiting, application site reactions, and anorexia. If ingested, hypersalivation may occur.


Avoid direct contact with application site for 4 hours or until visibly dry.


Esafoxolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in cats with or without a history of seizures. 


Use with caution in cats with a history of seizures or neurologic disorders.


The safety of NexGard® COMBO has been tested and is approved in breeding, pregnant, or lactating queen (cats) in the Philippines. The safety of the product has not been established in breeding male cats. 


NexGard® COMBO is for use in cats 8 weeks of age and older, weighing 0.8 kg or more.


For more information, click here for full prescribing information.


[i] Colella V, Nguyen VL, Tan DY, Lu N, Fang F, Zhijuan Y, et al. Zoonotic Vectorborne Pathogens and Ectoparasites of Dogs and Cats in Eastern and Southeast Asia. Emerg Infect Dis. 2020;26(6):1221-1233. Accessed April 2023.

[i] Rakuten Insight. Pet Ownership in Asia. Available from Accessed April 2023.

Little, S., and K. Duncan. "Ear mites: Uncovering, treating, and preventing infestations." Today's Veterinary Practice, 16 June 2021, Accessed 9 May 2023

4 American Veterinary Medical Association. Parasites in cats and dogs. Available from Accessed May 2023.



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